It is a technology that allows the use of the organism’s own resources with extraordinary results in many pathologies, effectively regenerating tissues without side effects and notably reducing the recovery period of fractures, muscular and tendinous injuries, and surgical interventions.

What are growth factors?

They are proteins that we all have and which carry out an essential function in complex processes of tissue repair and regeneration.

They are naturally found in the plasma of each individual and inside platelets. The therapeutic application of growth factors stimulates and accelerates the processes of tissue healing and regeneration.

What is Endoret®(prgf®) technology?

Endoret®(prgf®) Technology: It is the most advanced autologous Platelet-Rich Plasma system. It is based on the activation of the patient’s own platelets for the stimulation and acceleration of tissue healing and regeneration.

Experience and research

Pioneers in this technique and with the highest number of publications on the applications of plasma rich in growth factors in regenerative medicine.
What advantages does Endoret®(prgf®) offer?

  • 100% biocompatible, versatile and safe.
  • It is the market’s first 100% autologous technology.
  • Control over its activation and use.
  • A simple protocol: just one centrifugation.
  • A fast protocol: just 8 minutes of centrifugation and 20 minutes of preparation..
  • Its clinical efficiency in the stimulation of tissue healing and regeneration has been described in a large number of international articles.
  • It does not contain leucocytes, avoiding their proinflammatory activity.
  • Powerful bacteriostatic properties.
  • Excellent therapeutic potential in different clinical applications.
  • In none of the treatments carried out over the years have any undesired effects been observed.
  • What sets Endoret®(prgf®) Technology apart from other technologies in the market?


  • It is a pioneer (Patent no EP1066838) in the development of specific protocols for tissue regeneration.
  • It is backed by a large number of international scientific studies and publications.
  • It is the only technique that holds the obligatory health certifications required for each one of the following applications:
    • Healing of venous ulcers
    • Consolidation of bone fractures and grafts
    • Fixation of prostheses in the hip, knee, etc.
    • Oral implantology
    • Injuries and breakages of ligaments, muscles and tendons
    • Treatment of skin burns, injuries and lesions
    • Regeneration of aged skin

It is a versatile system that makes it possible to create different formulations that adapt to the characteristics of each application.
Excellent efficiency of the volume of blood extracted with this system.

Endoret®(prgf®) in orthopaedic surgery and sports medicine

As in oral and maxillofacial surgery, the application of Endoret®(prgf®) is obtaining very promising results in sports medicine and orthopaedics.

aplicaciones traumatologiaThe possibility of using Endoret® (prgf®) as a therapeutic alternative in the treatment of sports-related injuries has been revolutionary for the surgeons and specialists of this medical speciality, shortening the recovery periods of injuries to tendons and cartilage, non-hypertrophic pseudo-osteoarthritis, osteoarthritis of the knee or epicondylitis, among others.

Ultrasound-guided infiltrations of Endoret®(prgf®) in the damaged muscle promote healing and functional recovery. For its application specific protocols have been developed for each indication.

The promising results obtained with top-level sports players have led to a wide and numerous variety of clinical studies which prove the potential and safety of Endoret®(prgf®) in the treatment of various pathologies and how it generally accelerates the functional recovery of patients with less pain and more satisfaction.

Unidad de Terapia BiológicaBTI has developed jointly with Biological Therapy Unit (UTB), leaded by Dr. Mikel Sanchez, the Endoret®(prgf®) technology protocols and applications used in this field of medicine.

The rapid development of this appication is evidenced by many scientific publications. Endoret®(prgf®) was a pioneer in the use of Plasma Rich in Growth Factors in sports medicine and orthopaedics.


Wound healing

Of all the options there are in the market, of particular relevance are those that seek to stimulate skin regeneration through the use of growth factors extracted from the patient’s own plasma. The use of biologically active growth factors and an autologous fibrin matrix applied locally to damaged areas facilitates cell renewal and improves skin health in a more natural way. This technology, Endoret®(prgf®) technology, also contributes to the treatment of different dermatological complications and accelerates the healing process of chronic ulcers in a short period of time.


The appearance of chronic ulcers is a very common complication in a wide range of pathologies that has a negative impact on the quality of life of the affected patients and leads to situations in which the amputation of the extremity is inevitable. Clinical data prove the safety and effectiveness of Endoret®(prgf®) as a therapeutic treatment to accelerate the healing process of different types of chronic ulcers.

vascularTreatment with Endoret®(prgf®) has lead to spectacular results in tissues damaged by a lack of blood irrigation that require vascular surgery. Likewise, vascular ulcers show significant improvement with this treatment.


Within the general process of ageing, the ageing of skin is not an isolated process, but is part of a general process that includes all organs and systems. However, the importance we currently attach to our physical appearance is growing. This growing aesthetic awareness means that the interest in developing new products to help us improve the appearance of our skin has increased.


The idea of using Endoret®(prgf®) to treat facial ageing is the result of a wide range of basic and clinical observations concerning its beneficial effect after its application to other tissues. The capacity of Endoret®(prgf®) to activate the regeneration of tissues can counteract the degenerative changes that take place in the skin after the third decade of life, improving its tone and plasticity.

– See more at: http://bti-biotechnologyinstitute.com/us/regenerative-medicine/applications-endoret/dermatology/#sthash.VSkqUzyX.dpuf

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